Androgens

Dihydroboldenone

Also called 1-testosterone, this is a directly active androgen rather than a harmless precursor waiting for activation.

Receptor and animal pharmacology; evidence checked 2026-10-01

Also known as: 1-Testosterone · DHB

Practical use

Evidence interpretation and concrete review questions

Match the structure: Keep the 17-position group and any ester or methyl modification visible.
Check the endpoint: Organ weight is not a direct measure of human performance.
Reject unsupported rankings: The study does not provide a human comparison of long-term harms.

Direct activity of 1-testosterone

PubChem chemical identity; checked October 1, 2026

Additional primary or official source

Overview

The identity is 17β-hydroxy-5α-androst-1-en-3-one. Dihydroboldenone is distinct from boldenone, 1-androsterone and methyl-1-testosterone. Evidence for one of these should not be attached to another because their names overlap.

Risks and limitations

The primary experiment found increased liver weight alongside androgenic and muscle-related effects. It did not determine a human toxicity rate or prove that receptor selectivity prevents systemic harm.

How to read this

Anabolic-to-androgenic rankings from laboratory models are not clinical safety scores.

Research explained

Direct activity of 1-testosterone

Who was studied

Androgen-receptor binding/transactivation assays and animal organ-weight comparisons with testosterone propionate.

What was found

The parent steroid strongly activated the receptor without requiring prior metabolic conversion. Prostate, seminal-vesicle and levator ani growth were stimulated; liver weight increased as well.