Androgens
Bolasterone
A steroid whose modern analytical evidence identifies metabolites, not a demonstrated human enhancement benefit.
Rat and liver-microsome analytical research; evidence checked 2026-10-01
Practical use
Evidence interpretation and concrete review questions
- Resolve the spelling and structure
- Record the α/β designation when comparing these similarly named compounds.
- Check confirmation strength
- Ask which metabolites were verified with authentic reference material.
- Reject invented precision
- The paper supplies no human risk percentage or performance prediction.
Overview
Bolasterone is 7α,17α-dimethyltestosterone. Calusterone has the opposite configuration at position seven; they should not be treated as interchangeable names. The primary work reviewed here concerns bolasterone metabolism.
Risks and limitations
The selected experiments do not quantify human adverse effects. Detection in animal urine cannot establish a safe exposure, and similarities to another steroid cannot supply missing clinical safety data.
How to read this
This entry helps distinguish chemical identity, metabolite identification and treatment evidence—three questions often collapsed in compound marketing.
Research explained
Mapping bolasterone metabolites
Who was studied
Experiments in rat liver microsomes and urine from treated rats, analyzed by high-resolution liquid chromatography–mass spectrometry.
What was found
Researchers reported 18 metabolites: sixteen hydroxylated forms, one reduced product and one glucuronide. Two were confirmed against reference material; other structures relied on fragmentation interpretation.
What it cannot establish
Animal metabolism and tentative structural assignments do not establish human benefit, toxicity incidence or equivalent human metabolites.
Read the original studyConfirmed and proposed structures differ
A matching reference standard supports stronger identification than a plausible mass-fragment pattern alone.
Supporting sourceOne stereochemical change matters
The α versus β orientation at position seven distinguishes bolasterone from calusterone.
Supporting sourceClaims versus findings
Incorrect
Eighteen detected metabolites mean eighteen proven human effects.
The study mapped chemical products in experimental systems, not clinical outcomes.
Check the evidenceCommon questions
Can calusterone trial results be assigned to bolasterone?
No. They are distinct stereochemical identities and require separate evidence.
SourceSources
Mapping bolasterone metabolites
PubChem chemical identity; checked October 1, 2026
Sources checked 2026-10-01.
General education; not a personal treatment plan.