SARMs
Enobosarm (Ostarine)
An investigational SARM studied for changes in lean mass and physical function, including in older adults.
Human research / important limitations
Also known as: ostarine · MK2866 · GTx024
Practical use
Applying the explained evidence
- Where it fits
- An investigational SARM studied for changes in lean mass and physical function, including in older adults.
- Put the information into practice
- Study populations matter. Findings in older adults are not a forecast of gains in young resistance-trained people. Lean body mass is a measured outcome, not a synonym for newly built contractile muscle.
- Check the exact molecule
- Keep the named molecule separate from a broad category claim. Check whether a finding comes from a human intervention, laboratory mechanism or analytical test before interpreting it as a performance benefit.
- Keep this limit in view
- A relatively short trial in a specific population cannot settle long-term risks or quantify recreational bodybuilding outcomes.
Overview
Enobosarm is a nonsteroidal selective androgen-receptor modulator. Development programs investigate muscle-wasting conditions; that is a different setting from recreational physique use.
Risks and limitations
FDA warnings for SARM products include serious liver and other health risks. A positive trial result does not validate an online product’s identity, purity or long-term safety.
How to read this
Study populations matter. Findings in older adults are not a forecast of gains in young resistance-trained people. Lean body mass is a measured outcome, not a synonym for newly built contractile muscle.
Research explained
Phase II randomized trial
Who was studied
120 older men and postmenopausal women; 12 weeks, placebo controlled and blinded.
What was found
The study reported exposure-related increases in total lean body mass and improvement in physical function.
What it cannot establish
A relatively short trial in a specific population cannot settle long-term risks or quantify recreational bodybuilding outcomes.
Read the original studyWhy the participant group matters
Older men and postmenopausal women may differ from trained young adults in baseline muscle, hormones and response to an intervention. A result in the former group does not supply a reliable gain estimate for the latter.
Supporting sourceA development candidate is not an approved supplement
Investigational studies are part of testing a medicine. They do not validate retail products marketed under a familiar research name. FDA warns that SARM-marketed products can carry serious risks, including liver injury.
Supporting sourceCommon questions
Are ostarine and MK-2866 separate compounds?
They are common names used for enobosarm in this entry. Aliases are searchable but are not counted as additional compounds.
Sources
Sources checked 2026-09-28.
General education; not a personal treatment plan.